NHS Greater Glasgow & Clyde Area Drug and Therapeutics Committee
Greater Glasgow and Clyde Prescribing
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11 Eye

11.6 Treatment of glaucoma

11.6.1 Beta - blockers

Total Formulary
TIMOLOL MALEATE (eye drops)

Restrictions: Restricted to specialist initiation.

Prescribing Notes:

The preserved eye drops are the first choice preparation. However, long-acting preparations of timolol should be reserved only for patients with compliance issues. For preservative-free preparations of timolol, see the Total Formulary     

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/5516.htm

BETAXOLOL

Restrictions: Restricted to specialist initiation.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/5508.htm

CARTEOLOL

Restrictions: Restricted to specialist initiation.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/5510.htm

LEVOBUMOLOL

Restrictions: Restricted to specialist initiation.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/5512.htm

TIMOLOL MALEATE (TIOPEX) (single-dose eye gel)

Restrictions: Restricted to use in patients who have proven sensitivity to preservatives.

Prescribing Notes:

Timolol maleate preserved eye drops are considerd the first line topical beta-blocker for glaucoma (see preferred list)

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/5516.htm

11.6.2 Prostaglandin analogues and prostamides

Total Formulary
LATANOPROST (eye drops)

Restrictions: The preservative-free presentations are further restricted to use in patients who have proven sensitivity to the preservative benzalkonium chloride.

Prescribing Notes:

The preservative-containing eye drops are the first choice preparation.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/57520.htm

BIMATOPROST

Restrictions: Restricted to specialist initiation. Prescribing of the single-dose eye drop preparation is further restricted to use only in patients who have a proven sensitivity to the preservative benzalkonium chloride.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/112790.htm

TAFLUPROST

Restrictions: Restricted to specialist initiation. Restricted to use only in patients who cannot tolerate other prostaglandin preparations due to proven sensitivity to the preservative benzalkonium chloride.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/203885.htm

TRAVOPROST

Restrictions: Restricted to specialist initiation.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/106168.htm

11.6.3 Sympathomimetics

Total Formulary
BRIMONIDINE

Restrictions: Restricted to specialist initiation.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/59167.htm

11.6.4 Carbonic anhydrase inhibitors and systemic drugs

Total Formulary
ACETAZOLAMIDE

Restrictions: Restricted to specialist initiation.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/5519.htm

BRINZOLAMIDE

Restrictions: Restricted to specialist initiation.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/86263.htm

DORZOLAMIDE

Restrictions: Restricted to specialist initiation.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/37623.htm

11.6.5 Miotics

Total Formulary
PILOCARPINE

Restrictions: Restricted to specialist initiation.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/29690.htm

11.6.6 Combination preparations

Combination preparations that consist of drugs from different classes of glaucoma medicines are included in this sub-section.

Total Formulary
BIMATOPROST AND TIMOLOL

Restrictions: Restricted to specialist initiation. Preservative-free unit dose eye drops are further restricted to use only in patients who have proven sensitivity to preservatives.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/129670.htm

BRINZOLAMIDE AND BRIMONIDINE (SIMBRINZA)

Restrictions: Restricted to specialist initiation.

BNF Link: https://www.medicinescomplete.com/mc/bnf/current/PHP7020-brinzolamide.htm?q=brinzolamide&t=search&ss=text&p=1#_hit

BRINZOLAMIDE AND TIMOLOL (AZARGA)

Restrictions: Restricted to specialist initiation.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/202584.htm

BRIMONIDINE AND TIMOLOL

Restrictions: Restricted to specialist initiation.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/129337.htm

DORZOLAMIDE AND TIMOLOL

Restrictions: Restricted to specialist initiation. Preservative-free unit dose eye drops are restricted to patients in whom a combination of these two agents is appropriate and who have proven sensitivity to benzalkonium chloride.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/73176.htm

LATANOPROST AND TIMOLOL

Restrictions: Restricted to specialist initiation.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/201208.htm

TAFLUPROST AND TIMOLOL (TAPTIQOM) (preservative-free eye drops)

Restrictions: Use for the reduction of intraocular pressure in adults with open angle glaucoma or ocular hypertension who are insufficiently responsive to topical monotherapy with beta blockers is restricted to specialist initiation in patients who have proven sensitivity to preservatives.

TRAVOPROST AND TIMOLOL

Restrictions: Restricted to specialist initiation.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/129689.htm

11.6.7 Other agents for glaucoma and intra-ocular pressure

Total Formulary
APRACLONIDINE

Restrictions: Restricted to specialist initiation. Apraclonidine 0.5% eye drops are restricted to use on specialist advice only for short term adjunctive therapy of chronic glaucoma.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/5559.htm