Greater Glasgow and Clyde Medicines

Restrictions:

Restricted to specialist use in accordance with regional protocol for the indication below:

• Use in combination with chlorambucil or bendamustine for the treatment of patients with chronic lymphocytic leukaemia (CLL) who have not received prior therapy and who are not eligible for fludarabine-based therapy is restricted to specialist use in accordance with regional protocol in patients who would not be considered for bendamustine therapy and who would receive chlorambucil-based therapy

Prescribing Notes:

The treatment of adults with relapsed CLL in combination with fludarabine and cyclophosphamide is not recommended by SMC and is non-Formulary.

BNF Link

Restrictions:

Restricted to specialist use for the treatment of relapsing-remitting multiple sclerosis (RRMS) with active disease defined by clinical or imaging features in accordance with local protocol (in development).

Prescribing Notes:

Ofatumumab is available for use in the same positioning of the treatment pathway as ocrelizumab.

BNF Link