NHS Greater Glasgow & Clyde Area Drug and Therapeutics Committee
Greater Glasgow and Clyde Prescribing
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4 Central nervous system

4.3 Antidepressant drugs

4.3.1 Tricyclic and related antidepressant drugs

Total Formulary
CLOMIPRAMINE

Restrictions: Restricted to specialist initiation only.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/3305.htm

4.3.2 Monoamine-oxidase inhibitors

Total Formulary
MOCLOBEMIDE

Restrictions: Restricted to patients who have failed to respond to first line antidepressants.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/3349.htm

PHENELZINE

Restrictions: Restricted to patients who have failed to respond to first line antidepressants.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/3342.htm

TRANYLCYPROMINE

Restrictions: Restricted to specialist initiation only. Restricted to patients who have failed to respond to first line antidepressants.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/3347.htm#_3347

4.3.3 Selective serotonin re-uptake inhibitors

Preferred list
FLUOXETINE

Restrictions: Excludes fluoxetine 10mg capsules, which remain non-Formulary

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/3365.htm

Total Formulary

4.3.4 Other antidepressant drugs

Preferred list
MIRTAZAPINE

Restrictions: Restricted to second line therapy.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/65192.htm

Total Formulary
DULOXETINE

Restrictions: Restricted to psychiatrist initiation only as a third line therapy for major depressive episodes. The SMC has not recommended its use for generalised anxiety disorders.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/129245.htm

VENLAFAXINE

Restrictions: The immediate release preparation is restricted to use as third line agent for depression. The MR preparation is restricted to initiation on the advice of a consultant only. The CSM have advised that venlafaxine should not be used in children and adolescents under 18 years of age. The treatment of moderate to severe generalised social anxiety disorder/social phobia has not been accepted for use by SMC and is non-Formulary.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/27102.htm