GGC Medicines: Proton pump inhibitors

Key to symbols

The medicine should be initiated by, or on the advice of a specialist, but is suitable for continuation by a GP

The medicine should only be used and prescribed by a specialist

Indicates the preferred choice within a class or group of medicines

1.3. Antisecretory drugs and mucosal protectants

1.3.5. Proton pump inhibitors

Patients should be maintained on the lowest dose possible. Those with GORD without oesophagitis are encouraged to use PPIs "on demand". Measurement of serum-magnesium concentrations should be considered before and during prolonged treatment with a proton pump inhibitor, especially when used with other drugs that cause hypomagnesaemia or with digoxin.

Preferred List

LANSOPRAZOLE (CAPSULES)

Prescribing Notes:

Patients should be maintained on the lowest dose possible. Those with GORD without oesophagitis are encouraged to use lansoprazole 'on demand'.

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OMEPRAZOLE (CAPSULES)

Prescribing Notes:

Patients should be maintained on the lowest dose possible. Those with GORD without oesophagitis are encouraged to use omeprazole 'on demand'.

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Total Formulary

LANSOPRAZOLE (ORODISPERSIBLE)

Restrictions:

Restricted for specialist initiation in patients with narrow-bore feeding tubes.

Prescribing Notes:

For advice on administering lansoprazole via enteral feeding tubes please click here

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OMEPRAZOLE (DISPERSIBLE)

Restrictions:

Use is restricted to

- patients with narrow-bore feeding tubes

- patients in the immediate period (2 weeks) after barriatric surgery

Prescribing Notes:

The orodispersible preparations are considerably more expensive than omeprazole capsules and should not used unless necessary.

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OMEPRAZOLE (INFUSION)

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