Greater Glasgow and Clyde Medicines
Key to symbols The medicine should be initiated by, or on the advice of a specialist, but is suitable for continuation by a GP The medicine should only be used and prescribed by a specialist Indicates the preferred choice within a class or group of medicines
The medicine should be initiated by, or on the advice of a specialist, but is suitable for continuation by a GP
The medicine should only be used and prescribed by a specialist
Indicates the preferred choice within a class or group of medicines
8.3.4. Hormone antagonists

8.3.4.1. Breast cancer

Total Formulary
Specialist and GP
ANASTROZOLE

Restrictions:

Restricted to specialist initiation. Restricted to use on the advice of breast cancer specialists in accordance with regional protocols.

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Specialist and GP
EXEMESTANE

Restrictions:

Restricted to specialist initiation. Restricted to use on the advice of breast cancer specialists in accordance with regional protocols.

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Specialist Only
FULVESTRANT (FASLODEX) (injection)

Restrictions:

Restricted to specialist use in accordance with regional protocol for the treatment of postmenopausal women with oestrogen receptor positive, locally advanced or metastatic breast cancer for disease relapse on or after adjuvant anti-oestrogen therapy, or disease progression on therapy with an anti-oestrogen.

Prescribing Notes:

The following indication is not recommended by SMC and remains non-Formulary:

  • Treatment of oestrogen receptor positive, locally advanced or metastatic breast cancer in postmenopausal women not previously treated with endocrine therapy

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Specialist and GP
GOSERELIN

Restrictions:

For the management of advanced breast cancer (in pre- and peri- menopausal women), goserelin (but not Zoladex LA®) is approved where other treatments have failed.

Prescribing Notes:

For other indications, see sections 6.7.2 and 8.3.4.2

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Specialist and GP
LETROZOLE

Restrictions:

Restricted to specialist initiation. Restricted to use on the advice of breast cancer specialists in accordance with regional protocols.

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Specialist and GP
TAMOXIFEN

Restrictions:

Restricted to specialist initiation.

Prescribing Notes:

Excludes tamoxifen liquid.

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Specialist and GP
TRIPTORELIN (Decapeptyl SR) (injection)

Restrictions:

Use in combination with tamoxifen or an aromatase inhibitor, for adjuvant treatment of endocrine responsive early stage breast cancer in women at high risk of recurrence who are confirmed as pre-menopausal after completion of chemotherapy is restricted to specialist initiation in accordance with regional protocol (in development).

Prescribing Notes:

For other indications for triptorelin, see sections 6.7.2 and 8.3.4.2

BNF Link